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striatal_SPN_lib

This repository contains a library of striatal projection neurons used in the publication:

Lindroos and Hellgren Kotaleski 2020. Predicting complex spikes in striatal projection neurons of the direct pathway following neuromodulation by acetylcholine and dopamine. EJN

Code for simulating, analysing and plotting can be found here: https://github.com/robban80/striatal_SPN_lib and here: https://bitbucket.org/rlindroos/neuron/src/cholinergic_modulation/Complex_spike/

The models are built in NEURON+python https://www.neuron.yale.edu/neuron/

How to run the models

  1. install NEURON with python support
  2. compile the mechanisms in mechanisms/single (nrnivmodl or mknrndll)
  3. execute python example.py

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Library of biophysically detailed striatal projection neurons (Lindroos and Hellgren Kotaleski 2020)

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