Skip to content

Commit 1f92847

Browse files
Raphael-GazzottiRaphael-Gazzotti
authored
Merge pull request #407 from lauramble/in_depth_curation_chemicals
Add chemicals needed for in-depth curation
2 parents 68c1531 + 24b4156 commit 1f92847

13 files changed

Lines changed: 249 additions & 4 deletions

‎instances/latest/terminologies/molecularEntity/ATP.jsonld‎

Lines changed: 18 additions & 0 deletions
Original file line numberDiff line numberDiff line change
@@ -0,0 +1,18 @@
1+
{
2+
"@context": {
3+
"@vocab": "https://openminds.om-i.org/props/"
4+
},
5+
"@id": "https://openminds.om-i.org/instances/molecularEntity/ATP",
6+
"@type": "https://openminds.om-i.org/types/MolecularEntity",
7+
"definition": "Adenosine triphosphate (ATP) is a nucleoside triphosphate. [sourced from [Wikipedia](https://en.wikipedia.org/wiki/Adenosine_triphosphate)]",
8+
"description": "ATP provides energy to drive and support many processes in living cells, such as muscle contraction, nerve impulse propagation, and chemical synthesis. When consumed in a metabolic process, ATP converts either to adenosine diphosphate (ADP) or to adenosine monophosphate (AMP). (adapted from Wikipedia: https://en.wikipedia.org/wiki/Adenosine_triphosphate)",
9+
"interlexIdentifier": "http://uri.interlex.org/base/ilx_0780796",
10+
"knowledgeSpaceLink": "https://knowledge-space.org/wiki/CHEBI:15422#atp",
11+
"name": "ATP",
12+
"preferredOntologyIdentifier": "http://purl.obolibrary.org/obo/CHEBI_15422",
13+
"synonym": [
14+
"adenosine 5'-triphosphate",
15+
"adenosine triphosphate",
16+
"H4atp"
17+
]
18+
}

‎instances/latest/terminologies/molecularEntity/BAPTA.jsonld‎

Lines changed: 19 additions & 0 deletions
Original file line numberDiff line numberDiff line change
@@ -0,0 +1,19 @@
1+
{
2+
"@context": {
3+
"@vocab": "https://openminds.om-i.org/props/"
4+
},
5+
"@id": "https://openminds.om-i.org/instances/molecularEntity/BAPTA",
6+
"@type": "https://openminds.om-i.org/types/MolecularEntity",
7+
"definition": "BAPTA (1,2-bis(o-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid) is an aminopolycarboxylic acid with a high affinity for calcium. [sourced from [Wikipedia](https://en.wikipedia.org/wiki/BAPTA)]",
8+
"description": "BAPTA is a white solid. It is used in research to chelate Ca2+. It is a component of some fluorescent calcium ion indicators such as Calcium Green and Oregon Green 488 BAPTA-1 and -2 (OGB-1, OGB2). [adapted from Wikipedia (https://en.wikipedia.org/wiki/BAPTA)]",
9+
"interlexIdentifier": null,
10+
"knowledgeSpaceLink": null,
11+
"name": "BAPTA",
12+
"preferredOntologyIdentifier": "http://purl.obolibrary.org/obo/CHEBI_60888",
13+
"synonym": [
14+
"1,2-Bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid",
15+
"1,2-Bis(o-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid",
16+
"2,2',2'',2'''-[ethane-1,2-diylbis(oxy-2,1-phenylenenitrilo)]tetraacetic acid",
17+
"Bapeta"
18+
]
19+
}

‎instances/latest/terminologies/molecularEntity/D-AP5.jsonld‎

Lines changed: 27 additions & 0 deletions
Original file line numberDiff line numberDiff line change
@@ -0,0 +1,27 @@
1+
{
2+
"@context": {
3+
"@vocab": "https://openminds.om-i.org/props/"
4+
},
5+
"@id": "https://openminds.om-i.org/instances/molecularEntity/D-AP5",
6+
"@type": "https://openminds.om-i.org/types/MolecularEntity",
7+
"definition": "D-AP5 is the D-isomer of AP5, a chemical compound that is a selective NMDA receptor antagonist that competitively inhibits the ligand (glutamate) binding site of NMDA receptors. [adapted from [Wikipedia](https://en.wikipedia.org/wiki/AP5)]",
8+
"description": "The active isomer of AP5 is considered to be the D configuration. AP5 is sometimes used in conjunction with the calcium chelator BAPTA to determine whether NMDARs are required for a particular cellular process. AP5 has also been used to study NMDAR-dependent LTP in the mammalian hippocampus. [adapted from [Wikipedia](https://en.wikipedia.org/wiki/AP5)]",
9+
"interlexIdentifier": "http://uri.interlex.org/base/ilx_0100867",
10+
"knowledgeSpaceLink": null,
11+
"name": "D-AP5",
12+
"preferredOntologyIdentifier": "https://purl.obolibrary.org/obo/CHEBI_138644",
13+
"synonym": [
14+
"5-Phosphono-D-norvaline",
15+
"D-2-amino-5-phosphonopentanoic acid",
16+
"D-2-Amino-5-phosphonopentanoic acid",
17+
"D-2-amino-5-phosphonovaleric acid",
18+
"D-2-amino-5-phosphopentanoic acid",
19+
"D-2-amino-5-phosphovaleric acid",
20+
"D-AP-5 acid",
21+
"D-AP-5",
22+
"D-AP5 acid",
23+
"D-APV acid",
24+
"D-APV",
25+
"D-Norvaline, 5-phosphono-"
26+
]
27+
}

‎instances/latest/terminologies/molecularEntity/GTP.jsonld‎

Lines changed: 20 additions & 0 deletions
Original file line numberDiff line numberDiff line change
@@ -0,0 +1,20 @@
1+
{
2+
"@context": {
3+
"@vocab": "https://openminds.om-i.org/props/"
4+
},
5+
"@id": "https://openminds.om-i.org/instances/molecularEntity/GTP",
6+
"@type": "https://openminds.om-i.org/types/MolecularEntity",
7+
"definition": "Guanosine-5'-triphosphate (GTP) is a purine nucleoside triphosphate. [sourced from [Wikipedia](https://en.wikipedia.org/wiki/Guanosine_triphosphate)]",
8+
"description": "GTP is one of the building blocks needed for the synthesis of RNA during the transcription process. It also has a role as an activator of substrates in metabolic reactions and as a source of energy for protein synthesis and gluconeogenesis. GTP is essential to signal transduction, in particular with G-proteins, in second-messenger mechanisms where it is converted to guanosine diphosphate (GDP) through the action of GTPases. (adapted from Wikipedia: https://en.wikipedia.org/wiki/Guanosine_triphosphate)",
9+
"interlexIdentifier": "http://uri.interlex.org/base/ilx_0439625",
10+
"knowledgeSpaceLink": "https://knowledge-space.org/wiki/CHEBI:15996#gtp",
11+
"name": "GTP",
12+
"preferredOntologyIdentifier": "http://purl.obolibrary.org/obo/CHEBI_15996",
13+
"synonym": [
14+
"5'-GTP",
15+
"guanosine 5'-triphosphate",
16+
"guanosine 5'-triphosphoric acid",
17+
"guanosine triphosphate",
18+
"H4gtp"
19+
]
20+
}

‎instances/latest/terminologies/molecularEntity/GTPDisodiumSalt.jsonld‎

Lines changed: 3 additions & 3 deletions
Original file line numberDiff line numberDiff line change
@@ -11,9 +11,9 @@
1111
"name": "GTP, disodium salt",
1212
"preferredOntologyIdentifier": "https://pubchem.ncbi.nlm.nih.gov/compound/135818278",
1313
"synonym": [
14-
"Guanosine 5'-triphosphate sodium salt hydrate",
15-
"NaGTP",
1614
"5'-triphospho-guanosine; hydrate; sodium salt",
17-
"disodium;[[[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-oxidophosphoryl] hydrogen phosphate;dihydrate"
15+
"disodium;[[[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-oxidophosphoryl] hydrogen phosphate;dihydrate",
16+
"Guanosine 5'-triphosphate sodium salt hydrate",
17+
"Na2GTP"
1818
]
1919
}

‎instances/latest/terminologies/molecularEntity/QX-314.jsonld‎

Lines changed: 20 additions & 0 deletions
Original file line numberDiff line numberDiff line change
@@ -0,0 +1,20 @@
1+
{
2+
"@context": {
3+
"@vocab": "https://openminds.om-i.org/props/"
4+
},
5+
"@id": "https://openminds.om-i.org/instances/molecularEntity/QX-314",
6+
"@type": "https://openminds.om-i.org/types/MolecularEntity",
7+
"definition": "QX-314 is a quaternary lidocaine derivative, permanently charged, and lipophobic. [sourced from the [Merck website](https://www.sigmaaldrich.com/FR/fr/product/mm/552233)]",
8+
"description": "QX-314 is a blocker of voltage-sensitive Na+ conductance when applied intracellularly. It suppresses the generation of Na+-dependent spikes from inside the cell membrane, without affecting Ca2+ currents or glutamate-activated currents. (adapted from the Merck website: https://www.sigmaaldrich.com/FR/fr/product/mm/552233)",
9+
"interlexIdentifier": "http://uri.interlex.org/base/ilx_0523764",
10+
"knowledgeSpaceLink": "https://knowledge-space.org/wiki/CHEBI:46937#qx-314",
11+
"name": "QX-314",
12+
"preferredOntologyIdentifier": "http://purl.obolibrary.org/obo/CHEBI_46937",
13+
"synonym": [
14+
"(2-((2,6-dimethylphenyl)amino)-2-oxoethyl)-triethylazanium",
15+
"[2-[(2,6-dimethylphenyl)amino]-2-oxoethyl]-triethylazanium",
16+
"2-((2,6-Dimethylphenyl)amino)-N,N,N-triethyl-2-oxoethanaminium",
17+
"2-[(2,6-dimethylphenyl)amino]-N,N,N-triethyl-2-oxoethanaminium",
18+
"QX 314"
19+
]
20+
}

‎instances/latest/terminologies/molecularEntity/cesiumSulfate.jsonld‎

Lines changed: 23 additions & 0 deletions
Original file line numberDiff line numberDiff line change
@@ -0,0 +1,23 @@
1+
{
2+
"@context": {
3+
"@vocab": "https://openminds.om-i.org/props/"
4+
},
5+
"@id": "https://openminds.om-i.org/instances/molecularEntity/cesiumSulfate",
6+
"@type": "https://openminds.om-i.org/types/MolecularEntity",
7+
"definition": "Cesium sulfate (or caesium sulfate) is the cesium salt with the formula Cs2SO4. [adapted from [Wikipedia](https://en.wikipedia.org/wiki/Caesium_sulfate)]",
8+
"description": "Cesium sulfate is a white water-soluble solid that is used to prepare dense aqueous solutions for use in isopycnic (or 'density-gradient') centrifugation. [adapted from Wikipedia (https://en.wikipedia.org/wiki/Caesium_sulfate)]",
9+
"interlexIdentifier": "http://uri.interlex.org/ilx_0514068",
10+
"knowledgeSpaceLink": null,
11+
"name": "cesium sulfate",
12+
"preferredOntologyIdentifier": "https://pubchem.ncbi.nlm.nih.gov/compound/25137",
13+
"synonym": [
14+
"caesium sulfate",
15+
"caesium sulphate",
16+
"cesium sulphate",
17+
"Cs2O4S",
18+
"Cs2SO4",
19+
"dicesium sulfate",
20+
"dicesium;sulfate"
21+
]
22+
}
23+

‎instances/latest/terminologies/molecularEntity/gabazine.jsonld‎

Lines changed: 3 additions & 1 deletion
Original file line numberDiff line numberDiff line change
@@ -11,6 +11,8 @@
1111
"name": "gabazine",
1212
"preferredOntologyIdentifier": "http://id.nlm.nih.gov/mesh/2018/M0142643",
1313
"synonym": [
14-
"SR-95531"
14+
"SR 95531",
15+
"SR-95531",
16+
"SR95531"
1517
]
1618
}

‎instances/latest/terminologies/molecularEntity/monopotassiumPhosphate.jsonld‎

Lines changed: 24 additions & 0 deletions
Original file line numberDiff line numberDiff line change
@@ -0,0 +1,24 @@
1+
{
2+
"@context": {
3+
"@vocab": "https://openminds.om-i.org/props/"
4+
},
5+
"@id": "https://openminds.om-i.org/instances/molecularEntity/monopotassiumPhosphate",
6+
"@type": "https://openminds.om-i.org/types/MolecularEntity",
7+
"definition": "Monopotassium phosphate (MKP) is the inorganic compound with the formula KH2PO4 (potassium cation with a dihydrogen phosphate anion). [adapted from [Wikipedia](https://en.wikipedia.org/wiki/Monopotassium_phosphate)]",
8+
"description": "Monopotassium phosphate, is often used as a fertilizer, food additive, and buffering agent. This salt often cocrystallizes with dipotassium salt as well as with phosphoric acid. [adapted from Wikipedia (https://en.wikipedia.org/wiki/Monopotassium_phosphate)]",
9+
"interlexIdentifier": null,
10+
"knowledgeSpaceLink": null,
11+
"name": "monopotassium phosphate",
12+
"preferredOntologyIdentifier": "http://purl.obolibrary.org/obo/CHEBI_63036",
13+
"synonym": [
14+
"KDP",
15+
"KH2PO4",
16+
"MKP",
17+
"monobasic potassium phosphate",
18+
"monopotassium dihydrogen phosphate",
19+
"monopotassium monophosphate",
20+
"monopotassium phosphate",
21+
"potassium dihydrogen phosphate",
22+
"potassium phosphate monobasic"
23+
]
24+
}

‎instances/latest/terminologies/molecularEntity/phosphocreatineSodium.jsonld‎

Lines changed: 20 additions & 0 deletions
Original file line numberDiff line numberDiff line change
@@ -0,0 +1,20 @@
1+
{
2+
"@context": {
3+
"@vocab": "https://openminds.om-i.org/props/"
4+
},
5+
"@id": "https://openminds.om-i.org/instances/molecularEntity/phosphocreatineSodium",
6+
"@type": "https://openminds.om-i.org/types/MolecularEntity",
7+
"definition": "Phosphocreatine sodium is a compound of two sodiums with a phosphocreatine molecule.",
8+
"description": "Phosphocreatine is a phosphorylated form of creatine that serves as a rapidly mobilizable reserve of high-energy phosphates in skeletal muscle, myocardium and the brain to recycle ATP. [adapted from [Wikipedia](https://en.wikipedia.org/wiki/Phosphocreatine)]",
9+
"interlexIdentifier": null,
10+
"knowledgeSpaceLink": null,
11+
"name": "phosphocreatine sodium",
12+
"preferredOntologyIdentifier": "https://pubchem.ncbi.nlm.nih.gov/compound/9571077",
13+
"synonym": [
14+
"creatine phosphate disodium salt",
15+
"disodium phosphocreatine",
16+
"Na2-phosphocreatine",
17+
"phosphocreatine sodium salt",
18+
"sodium phosphocreatine"
19+
]
20+
}

0 commit comments

Comments
 (0)